Jump to content

Formimidoylglutamate deiminase

From Wikipedia, the free encyclopedia
formimidoylglutamate deiminase
Identifiers
EC no.3.5.3.13
CAS no.9054-85-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a formimidoylglutamate deiminase (EC 3.5.3.13) is an enzyme that catalyzes the chemical reaction

N-formimidoyl-L-glutamate + H2O N-formyl-L-glutamate + NH3

Thus, the two substrates of this enzyme are N-formimidoyl-L-glutamate and H2O, whereas its two products are N-formyl-L-glutamate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is N-formimidoyl-L-glutamate iminohydrolase. Other names in common use include formiminoglutamate deiminase, and formiminoglutamic iminohydrolase. This enzyme participates in histidine metabolism.

References

[edit]
  • Wickner RB, Tabor H (1971). N-Formimino-L-glutamate iminohydrolase (Pseudomonas sp.). Methods Enzymol. Vol. 17B. pp. 80–84. doi:10.1016/0076-6879(71)17012-7.